BPA Hormone Interference

Here’s a research report that may have direct bearing on our health. Specifically, ”BPA has been linked to problems with growth, metabolism, behavior, fertility and even greater cancer risk.” Afterwards, I’ll include some specific and easy-to-do actions you can take to avoid the problem.

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Study finds BPA levels in humans dramatically underestimated


Sara Zaske

WSU News

December 5, 2019


PULLMAN, Wash.—Researchers have developed a more accurate method of measuring bisphenol A (BPA) levels in humans and found that exposure to the endocrine-disrupting chemical is far higher than previously assumed.

The study, published in the journal The Lancet Diabetes & Endocrinology on Dec. 5, provides the first evidence that the measurements relied upon by regulatory agencies, including the U.S. Food and Drug Administration, are flawed, underestimating exposure levels by as much as 44 times.

Patricia Hunt, Washington State University professor and corresponding author on the paper, said …


“This study raises serious concerns about

whether we’ve been careful enough about

the safety of this chemical. What it comes

down to is that the conclusions federal agencies

have come to about how to regulate BPA may

have been based on inaccurate measurements.”


BPA can be found in a wide range of plastics, including food and drink containers, and animal studies have shown that it can interfere with the body’s hormones.  In particular …

fetal exposure to BPA has been linked to

problems with growth, metabolism,

behavior, fertility and even

greater cancer risk.

Despite this experimental evidence, the FDA has evaluated data from studies measuring BPA in human urine and determined that human exposure to the chemical is at very low, and therefore, safe levels. This paper challenges that assumption and raises questions about other chemicals, including BPA replacements, that are also assessed using indirect methods.

Hunt’s colleague, Roy Gerona, assistant professor at University of California, San Francisco, developed a direct way of measuring BPA that more accurately accounts for BPA metabolites, the compounds that are created as the chemical passes through the human body.

Previously, most studies had to rely on an indirect process to measure BPA metabolites, using an enzyme solution made from a snail to transform the metabolites back into whole BPA, which could then be measured.

Gerona’s new method is able to directly measure the BPA metabolites themselves without using the enzyme solution.

In this study, a research team comprised of Gerona, Hunt and Frederick vom Saal of University of Missouri compared the two methods, first with synthetic urine spiked with BPA and then with 39 human samples. They found much higher levels of BPA using the direct method, as much as 44 times the mean reported by the National Health and Nutrition Examination Survey (NHANES). The disparity between the two methods increased with more BPA exposure: the greater the exposure the more the previous method missed.

Gerona, the first author on the paper, said more replication is needed. He said …


“I hope this study will bring attention to the

methodology used to measure BPA, and that

other experts and labs will take a closer look

and assess independently what is happening.”


The research team is conducting further experiments into BPA measurement as well as other chemicals that may also have been measured in this manner, a category that includes environmental phenols such as parabens, benzophenone, triclosan found in some cosmetics and soaps, and phthalates found in many consumer products including toys, food packaging and personal care products. Gerona said…


“BPA is still being measured indirectly

through NHANES, and it’s not the only

endocrine-disrupting chemical being

measured this way. Our hypothesis

now is that if this is true for BPA, it

could be true for all the other chemi-

cals that are measured indirectly.”


This study was supported by grants from the National Institutes of Health. 

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The big question is:


How can you know whether or not BPA is

in the packaging of food you’re buying?


The answer:


Read the label !


Products are proud to state that their packaging does not contain harmful chemicals, such as BPA, and will state on their label “BPA Free.”

In addition …

Try to avoid plastic packaging as much as possible – which is not easy. Some packaging uses a corn-based product, most commonly on dried food such as potato chips or dried beans, and will state so on the package.  Such packaging also degrades after use … into a compost pile or even in waterways or the ocean.

For fresh produce, try to remember to bring your own bags. It’s less convenient, but leads to better health.  As “sustainable living” includes living joyfully, good health is certainly a part of that equation.

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