Organ Healing

Here’s some medical research that smacks a bit like that of doctor McCoy’s Star Trek technology and promises a more healthful and comfortable life for many of us. It’s a non-invasive, quick-acting method for healing organs – such as heart, liver, lungs – that have developed problems.

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Breakthrough Device Heals

Organs With A Single Touch



Ohio State University Medical Center


Researchers at The Ohio State University Wexner Medical Center and Ohio State’s College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells.

Results of the regenerative medicine study were published in the journal Nature Nanotechnology.


“By using our novel nanochip technology, injured

or compromised organs can be replaced. We have

shown that skin is a fertile land where we can

grow the elements of any organ that is declining.”


… said Dr. Chandan Sen, director of Ohio State’s Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State’s College of Engineering in collaboration with Ohio State’s Nanoscale Science and Engineering Center.

Researchers studied mice and pigs in these experiments. In the study, researchers were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved.

In lab tests, this technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke.


“This is difficult to imagine, but it is achievable,

successfully working about 98 percent of the time.

With this technology, we can convert skin cells

into elements of any organ with just one touch.


“This process only takes less than a second

and is non-invasive, and then you’re off.

The chip does not stay with you, and

the reprogramming of the cell starts.

Our technology keeps the cells in the

body under immune surveillance, so

immune suppression is not necessary.”


… said Sen, who also is executive director of Ohio State’s Comprehensive Wound Center.  TNT technology has two major components:


First is a nanotechnology-based chip designed

to deliver cargo to adult cells in the live body.


Second is the design of specific biological

cargo for cell conversion.


This cargo, when delivered using the chip, converts an adult cell from one type to another, said first author Daniel Gallego-Perez, an assistant professor of biomedical engineering and general surgery who also was a postdoctoral researcher in both Sen’s and Lee’s laboratories.

TNT doesn’t require any laboratory-based procedures and may be implemented at the point of care. The procedure is also non-invasive. The cargo is delivered by zapping the device with a small electrical charge that’s barely felt by the patient. Lee said:


“The concept is very simple. As a matter of fact,

we were even surprised how it worked so well.

In my lab, we have ongoing research trying to

understand the mechanism and do even better.

So, this is the beginning, more to come.”


Researchers plan to start clinical trials next year to test this technology in humans, Sen said.


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This type of technology offers several benefits. Greater health, of course. And perhaps greater longevity … even greater healthful longevity. And feeling great is definitely a part of joyful sustainable living.  Even more, perhaps, is a reduced fear of organ failure; it’s fear that eats at our quality of life experience. If my fingernails are too long … I clip them; no big deal and no fear. But if I discover some irregularities with my heart … ?

Clearly, the device is not yet at your “local neighborhood doctor’s office.” But it’s certainly worth tracking its approval and distribution, so you’ll know where to go should a need arise.

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